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Peng Yin Email: Phone: 626 395 8843. Fax: 626 395 8845 Office: 173 Broad, 342 Moore. Mail: Caltech 305-16 (Annenberg), Pasadena, CA 91125 |
I am a senior postdoctoral scholar in bioengineering and computer science at Caltech's Center for Biological Circuit Design, which is part of Caltech's Information Science and Technology initiative. At Caltech, I primarily work with Prof. Niles A. Pierce and Prof. Erik Winfree.
Before joining Caltech, I obtained a Ph.D. in computer science under Prof. John H. Reif and a M.Sc. in molecular cancer biology, both from Duke University. Before coming to Duke, I graduated from Peking University with a B.Sc. in biochemistry and molecular biology and a Bachelor in Economics.
My research interests lie at the interface of information science, molecular engineering, and biology. The current focus is to engineer information directed self-assembly of nucleic acid (DNA/RNA) structures and devices, and to exploit such systems to do useful molecular work, e.g. probing and programming biological processes for imaging and therapeutic applications.
My Curriculum Vitae can be found here.
Recent publications:
[The abstraction of a DNA hairpin motif is used to program diverse self-assembly (and disassembly) pathways. Paper download.]
[Highlighted in "The year in Nature", which features Nature manuscript editors' 22 favorites in 2008. See Caltech's news release and NSF's news realease. See excellent commentaries: "Biomolecular assembly: Dynamic DNA" by W. Shih in Nature Materials (pdf), "Rational engineering of dynamic DNA systems" by U. Feldkamp and C.M. Niemeyer in Angew. Chemie. (pdf), and "Tying new knots in synthetic biology" by D.K. Karig and M.L. Simpson in HFSP Journal (pdf). ]
[Synthetic molecular tubes with monodisperse, programmable circumferences are self-assembled using a single-stranded DNA motif. Paper download.]
[Highlighted in Nature Nanotechnology. See Caltech's news release. ]
Recent talks: